COVID-19 Vaccine Induced Thrombotic Thrombocytopenia

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There are over 1000 peer-reviewed papers in the preprint server system and or in the National Library of Medicine (PUBMED) describing side effects after mRNA or adenoviral DNA COVID-19 vaccination.  One of the most dreaded complications is vaccine-induced thrombotic thrombocytopenia (VITT).  

Because the Spike protein produced in response to the vaccine genetic code causes hemagglutination and micro blood clotting, there is excessive antigenic presentation of platelets to the spleen and reticuloendothelial system.  As a result, the body produces auto-antibodies directed against a platelet receptor (PF4) which has homology with an endothelial protein.

This causes autoantibody “pinning” of platelets to the lining of blood vessel cells resulting in consumption of platelets, blood clotting and bleeding at the same time.  Unfortunate victims are fine for a few weeks after vaccination.  Then bleeding from the oral and nasal mucosa associated with bruising under the skin occurs commonly with serious blood clotting within the brain and elsewhere in the body.

Most patients are hospitalized in critical condition as doctors try a variety of medical and interventional maneuvers to combat simultaneous clotting and bleeding.  As you can imagine, in some individuals the process is overwhelming and no matter how much critical care support is given, the patient dies.[i]   The obituary of Mrs. Jessica Berg, age 37, a previously healthy vibrant mother is given in the figure.[ii]   It indicates she died as a result of VITT.

Jessica Berg Wilson, Oct. 29, 1983 – Sept. 7, 2021, died of COVID-19 VITT

To her left is a paper by Tsilingiris et al, titled “Vaccine induced thrombotic thrombocytopenia:  The shady side of a success story.[iii]”

The authors never state what “success” meant in the title but it is clear that schools, employers, and the military are “shady” when they don’t fairly warn people what can happen when forcing mass vaccination.

Television commercials, internet promotions, and consent forms do not describe VITT.   Ms. Berg and her family had no way of getting an informed consent.  To her right is a treatment pathway described that doctors commonly take to treat patients in the hospital.  As in her case, many patients (~39%) succumb to this premature and bloody death which leaves more questions than answers.   How could this have been anticipated?   Is VITT associated with prior heparin induced thrombocytopenia (a similar syndrome)?  What is the best initial blood thinner?  Why aren’t patients with prior blood disorders given prompt exemption from such a horrific threat?  Ask your doctor next time about VITT and how would they advise to avoid it.   If you get a blank look or a queasy uncomfortable expression, show a copy of Ms. Berg’s obituary and start a critical conversation.

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Notes

[i] Sharifian-Dorche M, Bahmanyar M, Sharifian-Dorche A, Mohammadi P, Nomovi M, Mowla A. Vaccine-induced immune thrombotic thrombocytopenia and cerebral venous sinus thrombosis post COVID-19 vaccination; a systematic review. J Neurol Sci. 2021 Sep 15;428:117607. doi: 10.1016/j.jns.2021.117607. Epub 2021 Aug 3. PMID: 34365148; PMCID: PMC8330139.

[ii] Obituary, Jessica Berg Wilson age 37

[iii] Tsilingiris D, Vallianou NG, Karampela I, Dalamaga M. Vaccine induced thrombotic thrombocytopenia: The shady chapter of a success story. Metabol Open. 2021 Sep;11:100101. doi: 10.1016/j.metop.2021.100101. Epub 2021 Jun 18. PMID: 34179744; PMCID: PMC8217988.

Featured image is from FiercePharma


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